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Hydrocodone/acetaminophen
Medication

Description

Hydrocodone/paracetamol is the combination of the pain medications hydrocodone and paracetamol. It is used to treat moderate to severe pain. It is taken by mouth. Recreational use is common in the United States. Common side effects include dizziness, sleepiness, constipation, and vomiting. Wikipedia

ChemSpider ID: 9422965
Other names: Hydrocodone/acetaminophen, hydrocodone/APAP
Metabolism: Hydrocodone: extensively liver, primarily CYP3A4; /Paracetamol: liver, CYP2E1
Paracetamol: Anilide analgesic
Elimination half-life: for hydrocodone: 228–294 mins (3.8–4.9 hrs); for paracetamol: 120–240 mins (2–4 hrs)
Excretion: for hydrocodone: urinary; for paracetamol: urinary (10–15% unchanged)
License data: US DailyMed: Hydrocodone_and_acetaminophen
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